TecHotSpots-Surv HotSpots Database



Sample Type
Cancer Type Gene Position HAZARD RATIO n With Hotspot n Without Hotspot Transcript pValorate pCoxHotSpot pCoxExtendido pCoxClinico pCoxMutCount p HS cox p HS cox Ext p HS cox Clinic p HS cox Mutation Count qValorate qCoxHotSpot qCoxExtendido qCoxClinico q HS cox q HS cox Ext q HS cox Clinic q HS cox Mutation Count
The information about the colums shown in the Hotspot table are:
CancerOfficial TCGA study abbreviations
TypeSample type codes from TCGA
GeneOfficial gene symbol
PositionAmino acid position
Hazard RatioHazard Ratio from Extended Cox Model
n with HotspotNumber of patients with Hotspot
N without HotspotNumber of patients without Hotspot
pValorateThe p value of the VALORATE statistical test
TranscriptEnsembl transcript code
p HS coxThe p value of the hotspot in the cox model
p HS cox ExtThe p value of the hotspot in the extended cox model
p HS cox ClinicThe p value of the hotspot in the clinic cox model
p HS cox Mutation CountThe p value of the hotspot in the Mutation cox model
qValorateThe false discovery rate (FDR) correction of the p-value of pVALORATE
q HS coxThe false discovery rate (FDR) correction of the p-value of pHScox
q HS cox ExtThe false discovery rate (FDR) correction of the p-value of pHScoxExtendido
q HS cox ClinicThe false discovery rate (FDR) correction of the p-value of pHScoxClinico
q HS cox Mutation CountThe false discovery rate (FDR) correction of the p-value of pHScoxMutCount

Test 1:

The hotspot is compared with other hotspots within the same gene per cancer type.

Test 2:

The hotspot is compared with other mutations within the same gene (even though it isn't a hotspot) per cancer type.

Test 3:

The hotspot is compared with other mutations of all patient's mutations per cancer type.

Test 4:

The hotspot is compared with another hotspot of the same gene per cancer type.